Substance
Abuse v. Dependence
Psychoactive Substance Abuse (DSM-IV Criteria):
Reference: DSM-IV, pages 182-3.
Psychoactive Substance Dependence (DSM-IV Criteria):
A maladaptive pattern of substance use, leading to clinically significant impairment or distress, as manifested by 3 (or more) of the following, occurring at any time in the same 12-month period:
a need for markedly increased amount of the substance to achieve intoxication…
markedly diminished effect with continued use of the same amount of the substance.
the characteristic withdrawal syndrome for the substance… or
the same (or a closely related) substance is taken to relieve or avoid withdrawal symptoms
- C: multiple attempts to Cut back or control substance use.
- Eye opener: substance taken to avoid withdrawal.
- L: Larger amounts or longer period of substance use than intended.
- T: Time spent seeking or thinking about the substance.
- W: Interference with Work or other important obligation (e.g., childcare)
- P: continued drinking despite medical, financial, or other significant substance-related Problems related to substance use. If
- Tolerance: increased dose required for same effect.
- Withdrawal symptoms.
Substance Dependence usually (but not always) involves physiological dependence, characterized by tolerance (higher doses of the substance required to achieve the same effect) and withdrawal ("rebound" symptoms upon sudden discontinuation of the substance). The main, "bottom line," criterion is continued use despite adverse consequences of use.
According to the Diagnostic and Statistical Manual, the only substance that cannot be diagnosed as causing substance dependence is caffeine. The only substance that cannot be diagnosed as causing abuse is nicotine (it can only be coded as dependence).
Who Uses Substances? According to recent surveys:
90% of Americans use alcohol in some form;
80% use caffeine;
25% use nicotine;
7% use some type of illicit drug.
Why Do People Use Substances? Most psychoactive substances, according to Wise (1988) activate areas of the brain that are powerfully linked to reward and reinforcement, such as the ventral tegmental area, the medial forebrain bundle, and the nucleus accumbens.